Since the highway system was built most roads that once were the main routes for the traveling public has faded away. Many of the old motels, drive-ins and tourist traps have faded away.
One road that I like to travel and practice my photography is Route 301 from Ocala to the Fla/Ga border. This is a long one day roundtrip. There are some great roadside stands and these two examples of old Florida. The Orange Shop in Citra is one of the very few old orange roadside stands. This is in Citra, Fl. The taxidermy shops location escapes me right now, however I do not recall seeing any others in Florida. There are many neat things to shoot on this stretch of road.